Fig 3.
Behavioral and cancer screening changes specifically motivated by personal genomic testing (PGT) risk for (A) breast cancer, (B) colorectal cancer, and (C) prostate cancer. Adjusted proportions and odds ratios from multivariable logistic regression are shown. All models are adjusted for age, race, ethnicity, sex, education, employment, household income, family history of cancer, health insurance, health status, and baseline behavior. Baseline behavior was defined by participant reports of fruit and vegetable consumption (diet); number of days of leisure-time physical activity (exercise); use of vitamins or herbal supplements; and mammography, colonoscopy, or prostate-specific antigen (PSA) testing within the year before testing. Of note, there was no baseline item that specifically pertained to advanced planning. All models except for the mammography, colonoscopy, or PSA outcome are adjusted further for PGT risk for type 2 diabetes, obesity, and coronary heart disease. The model for the mammography outcome is adjusted further for interest in genetic risk for breast cancer and baseline perceived risk for breast cancer. The model for the colonoscopy outcome is adjusted further for interest in genetic risk for colorectal cancer and baseline perceived risk for colorectal cancer. The model for the PSA outcome is adjusted further for interest in genetic risk for prostate cancer and baseline perceived risk for prostate cancer.