. 2017 Jun 2;12(6):e0178086. doi: 10.1371/journal.pone.0178086

Table 6. Correlation between histologic assessment of synovial inflammatory cell populations and arthroscopic assessment of cranial cruciate ligament fiber damage.

	Histologic Synovitis VAS		Suppurative Inflammation Grade		CD3⁺ T-Lymphocyte Grade		TRAP⁺ Macrophage Grade		Factor VIII⁺ Vessel Grade		Synovial Factor VIII⁺ Vessel VAS
	S_R	P value	S_R	P value	S_R	P value	S_R	P value	S_R	P value	S_R	P value
Complete CR Stifle
Histologic Synovitis Grade	0.62	0.0003	0.02	0.91	0.20	0.31	0.06	0.74	0.05	0.80	0.03	0.88
Histologic Synovitis VAS	n/a		0.16	0.41	0.16	0.40	0.05	0.78	0.20	0.31	0.08	0.68
Partial CR Stifle
Histologic Synovitis Grade	0.79	<0.0001	0.07	0.72	0.38	0.05	0.46	0.01	0.16	0.41	0.04	0.83
Histologic Synovitis VAS	n/a		0.002	0.99	0.30	0.13	0.50	0.007	0.32	0.11	0.29	0.14
Arthroscopic Fiber Damage VAS	0.38	0.04	0.02	0.91	0.35	0.07	0.16	0.40	0.34	0.09	0.36	0.06

Note: Arthroscopic fiber damage VAS assesses ligament fiber rupture in the cranial cruciate ligament in the partial CR stifle. n = 28–29 dogs. Abbreviations: CR, cruciate ligament rupture; CrCL, cranial cruciate ligament; VAS, visual analog scale score.