TABLE 2.

Selected genes exhibiting different expression profiles in response to mitomycin C and hydrogen peroxide treatment in Salmonella and E. coli^a

Gene(s) or operon(s)	LT2, mitomycin C	LT2, H2O2	CT18, H2O2	E. coli, mitomycin C	E. coli, H2O2c
Amino acid transport and metabolism
gltI-L, metA-J, smvA	↓b	↑	↑	O
gcvTHRP	↑	O/↑	↓	↑
tyrR glpB	↓	↓	↑	O
potA-I	O	↑	↓/O	O
sdaABC	↑	↑	↓	↓
Carbohydrate transport and metabolism
malGEFKSTZ, manAXYZ	↓	↓	O	↑	↑
mglABC	↑	↓	O	↑
ptsGHI	↓	↑	↓	↓
fba	↑	↑	↓	↑
glgABPSX, nagABDET	↓	↓	↑	↑	↑
Cell envelope and surface structures
rfbA-Z, rfaA-Z	↓	↑	O	O
ompX	↑	↑	↓	↑
fimA-Z, safA-D stiA-H, stdABC, stfA-G, stcA-E	O/↓	↑	O/↓
Cell motility and secretion
fliA-Z, motAB, cheABRWYZ	↑	↑	O	O
flgABCDEFGHIJKLMN	↑	↓	O	O
Energy production and conservation
glpABCDEFTQ, napABCDFH, narHIJKLPQXVWZ	↓	↓	↑	O/↑
atpA-I	↑	↑	↓	O
aceEF, lpdA	↑	↑	O/↓	O/↓
adhE, hycABCDEFGHI	↓	↑	O/↓	O/↑
frdABCD	↓	↓	O	↑
fdhF	↓	↑	↑	O
Global regulatory function and transcription
rpoN, rho	↑	↑	↓	O/↓
phoPQ	↑	↓	↓	O
lrp, arcA	↑	↑	O	O
lon	O	↑	↓	O
lexA,	↑	↑	↑	O
phoBR	O	↑	↑	↑
oxyR	O	O	O	↑
soxSR	↓	↑	↑	O	↑
nifU	↑	↑	O
rseABC	O	O	↑	O
Inorganic ion transport and metabolism
modABCEF	O/↑	↑	O/↑	O
fepABCDEG, fes, fhuABCDE	↓	↑	↑	O/↓
katE	O	↑	O	↑
katG	↓	↓	↑	↑	↑
ydiE	↓	↑	↑	O
narK, nirCD, nrfDA	↓	↓	O	O
Lipid metabolism
accABCD, fadABDEFHILZ	↑	↑	↓	↓
SPI1
invA-J, sipA-D, prgHIJK	↑	↓	↓
spaO-S	↑	O	O
sitA-D	O	↑	↑
SPI2
ssaA-V, ssrAB, sseA-G	O/↓	↑	↑
Translation ribosome structure and biogenesis
rplA-Y, rpmA-G, rpsA-V, infABC, tufAB	↑	↑	↓	O	O

^aData were compiled from this study and references 12, 19, 20, and 29.

^b↑, increased expression compared to untreated control; ↓, decreased expression compared to untreated control; O, no difference compared to untreated control.

^cOnly data published by Zheng et al. (29) are shown.