Table 2. Associations between types and intensity of physical activity and prostate cancer risk in the South and East China case control study on prostate and bladder cancer (SEARCH).
| Overall Associations |
Age category (years) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Activitya | Level | MET | Cases | Controls | Univariate | Age adjusted | multivariableb | < 65b | ≥ 65b | |
| (h/wk) | (N = 260) | (N = 336) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | Phet | ||
| All types of | Low | < 73.5 | 112 | 111 | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | |
| physical | Medium | 73.5–166.2 | 98 | 113 | 0.70 (0.43–1.14) | 0.71 (0.43–1.17) | 0.69 (0.41–1.16) | 0.31 (0.09–1.08) | 0.80 (0.43–1.47) | |
| activity | High | 166.3–383.3 | 50 | 112 | 0.35 (0.20–0.61) | 0.54 (0.30–0.99) | 0.53 (0.28–0.98) | 0.58 (0.17–2.01) | 0.50 (0.24–1.03) | |
| Ptrend for linearity | <0.001 | 0.05 | 0.04 | 0.13 | 0.05 | 0.22 | ||||
| Vigorous | None | 0 | 103 | 110 | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | |
| physical | Medium | 1–70 | 105 | 115 | 0.85 (0.54–1.32) | 0.94 (0.59–1.51) | 0.89 (0.55–1.45) | 0.91 (0.32–2.57) | 1.01 (0.57–1.77) | |
| activity | High | 71–315 | 52 | 111 | 0.44 (0.26–0.72) | 0.78 (0.44–1.38) | 0.71 (0.39–1.28) | 0.57 (0.20–1.61) | 0.78 (0.38–1.57) | |
| Ptrend for linearity | <0.001 | 0.46 | 0.31 | 0.36 | 0.59 | 0.77 | ||||
| Moderate | Low | < 42 | 108 | 93 | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | |
| physical | Medium | 42–62 | 53 | 90 | 0.46 (0.28–0.77) | 0.38 (0.22–0.66) | 0.30 (0.17–0.54) | 0.04 (0.01–0.37) | 0.39 (0.21–0.69) | |
| activity | High | 63–210 | 99 | 153 | 0.49 (0.29–0.81) | 0.52 (0.30–0.90) | 0.45 (0.26–0.79) | 0.38 (0.16–0.90) | 0.48 (0.28–0.81) | |
| Ptrend for linearity | 0.007 | 0.03 | 0.02 | 0.01 | 0.01 | 0.17 | ||||
| Walking | Low | <10.5 | 85 | 57 | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | |
| Medium | 10.5–20 | 48 | 54 | 1.80 (1.06–3.05) | 1.54 (0.87–2.74) | 1.52 (0.84–2.74) | 1.04 (0.36–2.99) | 1.81 (0.86–3.81) | ||
| High | 21–84 | 203 | 149 | 1.30 (0.79–2.16) | 1.05 (0.60–1.82) | 0.93 (0.52–1.66) | 0.61 (0.21–1.80) | 0.87 (0.45–1.71) | ||
| Ptrend for linearity | 0.44 | 0.93 | 0.62 | 0.37 | 0.39 | 0.63 | ||||
| Cycling | Never | — | 206 | 326 | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | |
| <1 hour/wk | — | 32 | 37 | 0.78 (0.40–1.52) | 1.19 (0.59–2.42) | 1.28 (0.61–2.67) | 3.02 (1.01–9.05) | 1.27 (0.50–3.19) | ||
| > = 1 hour /wk | — | 22 | 64 | 0.42 (0.24–0.72) | 1.04 (0.54–1.98) | 1.18 (0.61–2.30) | 0.68 (0.23–1.97) | 1.56 (0.62–3.90) | ||
| Ptrend for linearity | 0.002 | 0.93 | 0.65 | 0.41 | 0.35 | 0.38 | ||||
a Activity measured by International Physical Activity Questionnaire (IPAQ) short form. Categories Low, Medium, and High are based on nearest tertile cut-off points among controls.
b Random effects logistic regression with hospital considered as random effect, adjusted for age, height, weight, smoking status, smoking duration and educational level, and health insurance.