Table 3. Combined associations of body size and serum hs-CRP levels with HOMA-IR.
| Body size | |||||
|---|---|---|---|---|---|
| Normal | Overweight | Obesity | * Pinteraction | ||
| (BMI<23.0 kg/m2) | (BMI 23.0~24.9 kg/m2) | (BMI>25.0 kg/m2) | |||
| Geometric adjusted means (95% confidence intervals) of HOMA-IR | |||||
| Model 1 | |||||
| Hs-CRP | |||||
| ≤median | 0.92 (0.87, 0.97) | 1.16 (1.04, 1.28) | 1.42 (1.27, 1.60) | <0.001 | |
| >median | 0.91 (0.84, 0.98) | 1.27 (1.16, 1.39) | 2.10 (1.95, 2.25) | ||
| Model 2 | |||||
| Hs-CRP | |||||
| ≤median | 0.93 (0.87, 0.98) | 1.16 (1.05, 1.29) | 1.44 (1.28, 1.63) | <0.001 | |
| >median | 0.93 (0.86, 1.00) | 1.28 (1.17, 1.41) | 2.13 (1.98, 2.29) | ||
hs-CRP, high-sensitivity C-reactive protein; HOMA-IR,homeostasis model assessment-insulin resistance
The median of hs-CRP was 0.30 mg/L.
Model 1: adjusted for age and sex
Model 2: adjusted for age, sex, recruit group, smoking habit, current alcohol drinking, leisure-time exercise, and daily energy intake
* P values for interaction between body size (3 categories; normal, overweight, and obesity) and serum hs-CRP (dichotomous; ≤median, >median) on HOMA-IR