Table 2. Independent and interactive effects of age and diet on outcome measures in young, early middle-age and late middle-age mice.

Measure	Diet	Aging	Interaction
Body weight	F(1,35) = 30.39, p< 0.05	F(2,35) = 3.72, p< 0.05	F(2,35) = 1.85, p = 0.17
Retroperitoneal fat	F(1,34) = 30.89, p< 0.05	F(2,34) = 3.26, p = 0.051	F(2,34) = 5.10, p< 0.05
Visceral fat	F(1,34) = 26.59, p< 0.05	F(2,34) = 3.64, p< 0.05	F(2,34) = 2.78, p = 0.08
Fasting glucose	F(1,35) = 15.18, p< 0.05	F(2,35) = 1.49, p = 0.24	F(2,35) = 1.19, p = 0.32
β-Amyloid load	F(1,28) = 0.82, p = 0.37	F(2,28) = 5.73, p< 0.05	F(2,28) = 0.78, p = 0.47
Spontaneous alternation	F(1,24) = 0.19, p = 0.67	F(2,24) = 1.56, p = 0.23	F(2,24) = 2.36, p = 0.11
Microglial activation	F(1,34) = 3.93, p = 0.06	F(2,34) = 101.6, p< 0.05	F(2,34) = 4.44, p< 0.05