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Model of the Snm secretion pathway in M. smegmatis. See Discussion for details of the model. CM, cytoplasmic membrane; PG, peptidoglycan layer; mAG, mycolyl arabinogalactan layer. Transmembrane domains were predicted by TMHMM (http://www.cbs.dtu.dk/services/TMHMM-2.0/), and topology is inferred based on predicted function and some experimental evidence (6).
