Table 2.
Combinations of sub-fractions | C. albicans NR-29450 | C. albicans | C. glabrata | C. parapsilosis | Cr. neoformans | |||||
---|---|---|---|---|---|---|---|---|---|---|
FICI | Int | FICI | Int | FICI | Int | FICI | Int | FICI | Int | |
C2/C12 | 1.06 | I | 1.06 | I | 1.06 | I | 1.00 | A | 0.62 | A |
C2/C22 | 0.75 | A | 0.50 | S | 0.75 | A | 0.62 | A | 0.31 | S |
C2/C24 | 0.56 | A | 0.75 | A | 0.75 | A | 0.53 | A | 0.31 | S |
C2/C26 | 0.62 | A | 0.75 | A | 0.75 | A | 1.12 | I | 0.62 | A |
C2/C32 | 0.56 | A | 1.12 | I | 0.75 | A | 1.00 | A | 0.37 | S |
C36/C2 | 0.50 | A | 0.62 | A | 0.50 | S | 0.50 | S | 0.50 | S |
C36/C12 | 0.37 | S | 0.62 | A | 0.56 | A | 0.37 | S | 0.25 | S |
C36/C22 | 0.53 | A | 0.62 | A | 0.75 | A | 0.75 | A | 0.37 | S |
C36/C24 | 1.00 | S | 1.12 | I | 0.50 | S | 0.75 | A | 0.50 | S |
C36/C26 | 0.75 | A | 0.75 | A | 0.62 | A | 0.56 | A | 0.25 | S |
C36/C32 | 0.62 | S | 0.50 | S | 0.75 | A | 0.56 | A | 0.62 | A |
FICI: Fractional Inhibitory Concentration Index; Int: interaction; I: indifference; A: additivity; S: synergy; C2: Te CL H2O/EthOH Fr H2O sFr CH3OH; C12: Te ML H2O Fr CH2Cl2 sFr CH3OH; C22: Te MSb H2O Fr H2O sFr CH3OH; C24: Te MSb H2O Fr CH2Cl2 sFr CH3OH; C26: Te MSbH2O/EthOH Fr H2O sFr CH3OH; C32: Te MSb EthOH Fr CH2Cl2 sFr CH3OH; C36: Mo TL EthOH Fr CH2Cl2 sFr CH3OH.