Table 4.
Selected target mRNAs of miRNA-148a.
| Target | Reported Biological Effects of miRNA-148a | References |
|---|---|---|
| DNMT1 | Reduced maintenance DNA methylation during cell division | [118,244] |
| DNMT3B | Reduced de novo DNA methylation | [121] |
| ABCA1 | Reduced reverse cholesterol transport, risk of dyslipidemia | [106] |
| LDLR | Reduced hepatic uptake of LDL, risk of dyslipidemia | [106] |
| CPT1A | Reduced mitochondrial fatty acid β-oxidation, risk of dyslipidemia | [106] |
| MIG6 | Reduced inhibition of EGFR, increased cell proliferation | [278] |
| ROCK1 | Reduced suppression of myogenesis, enhanced myogenesis | [261] |