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Open field exploration. Normal (grey bars), MPS I untreated mice (black solid bars) and MPS I mice treated with rhodamine B (black hatched bars) were tested in the open field apparatus over a period of 3 min at 6 months of age. Rearing events were recorded and data is expressed as average + SEM for each group. * indicates significantly different from normal (p < 0.05, one-way ANOVA, Tukey’s post-hoc test).
