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. 2017 Feb 23;5(1):5. doi: 10.3390/diseases5010005

Figure 6.

Figure 6

Water cross maze testing to assess spatial learning and memory. Sex separated correct entries analysis assessed in the water cross maze at 4 months of age in normal mice (grey bars), MPS I untreated mice (black solid bars) and MPS I mice treated with rhodamine B (black hatched bars). Correct entry learning and memory data combined is presented for female (A) and male (B) mice. Results are expressed as average + SEM of six trials for each mouse tested. * and ** indicate significantly different from normal (p < 0.05 and p < 0.001 respectively, one-way ANOVA, Tukey’s post-hoc test). # indicates significant difference in MPS I treated versus MPS I untreated mice (p < 0.05, one-way ANOVA, Tukey’s post-hoc test).