Table 2.
β-hexosaminidase enzyme activity levels.
| Normal | MPS I Untreated | MPS I SDT | |
|---|---|---|---|
| Brain | 184.26 ± 13.74 | 1102.85 ± 98.46 ** | 987.06 ± 84.54 ** |
| Liver | 1009.92 ± 103.21 | 9169.05 ± 443.00 ** | 8975.07 ± 488.27 ** |
| Kidney | 859.83 ± 0.58 | 5857.89 ± 11.67 ** | 7239.73 ± 0.001 ** |
| Spleen | 3285.37 ± 380.58 | 5094.60 ± 485.28 * | 4412.64 ± 329.73 |
| Heart | 241.51 ± 23.76 | 5118.18 ± 338.74 ** | 4885.17 ± 414.17 ** |
| Lung | 404.69 ± 54.90 | 6068.17 ± 460.39 ** | 5755.82 ± 453.01 ** |
β-hexosaminidase enzyme levels are expressed as the average ± SEM for each group. Results are presented as nmol/min/mg tissue. * indicates p < 0.05, One-way ANOVA, Tukey’s post-hoc test, Normal vs. MPS I. ** indicates p < 0.001, One-way ANOVA, Tukey’s post-hoc test, Normal vs. MPS I untreated or Normal vs. MPS I SDT.