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. 2017 Jun 2;12(6):e0178762. doi: 10.1371/journal.pone.0178762

Table 1. Characteristics of the studies included in the meta-analysis.

Author Year Country Region Follow-up (months) Treatment No. of patients Stage Cut-off value Survival
analysis
Analysis NOS
score
Shirai 2015 Japan Asia NA Surgery 150 No-metastatic 150 OS MV/UV 6
Smith 2009 UK Europe 12(7.8–25.5) Surgery 110 No-metastatic 150 OS MV 6
Qi 2015 China Asia NA Chemotherapy 211 Metastatic 126 OS MV/UV 7
Martin 2014 Austria Europe 12 Mixed 124 Metastatic 200 OS MV/UV 8
Kou 2016 Japan Asia 10.8(1.7–72.1) Chemotherapy 306 Metastatic 150 OS UV 7
Lnoue 2014 Japan Asia 18.7(6.1–68.2) Mixed 440 Mixed 150 OS MV/UV 8
Asari 2016 Japan Asia 18(10–35) Surgery 184 Mixed 225 OS MV/UV 6
Yamada 2016 Japan Asia 15.1(0.43–150.7) Surgery 379 Mixed 150 OS MV/UV 8

OS: overall survival; MV: multivariate; UV: univariate; NA: not available