Fig 2. The increase in liver stiffness (ΔTE) defines the development of CFLD in pediatric patients.
(A) The receiver operating characteristics (ROC) analysis identified a consistent increase of liver stiffness in 9 of 10 pediatric patients with a TE(4–5) >6.3 kPa and fixed the cut-off as rationale for grouping ΔTEcut-off = 0.38 kPa/year. The frequency of CFLD (B), the enhancement of liver stiffness ΔTE (C), and the median stiffness (D) was increased in the TEinc-group compared to the TEcon-group.
