Table 2.
Normalized amount of extracellular matrix constituents secreted and deposited by a human osteosarcoma cell line (SAOS-2) cells cultivated for 10 d on PLGA and PLGA/Ag samples (pg/Cell × Sample).
| Matrix Protein Deposition after 10 d of Cell Culture Expressed as pg/(cell × well) | |||||||
|---|---|---|---|---|---|---|---|
| Samples | PLGA | PLGA/1Ag | Ratio PLGA/1Ag and PLGA | PLGA/3Ag | Ratio PLGA/3Ag and PLGA | PLGA/7Ag | Ratio PLGA/7Ag and PLGA |
| Alkaline Phosphatase | 2.9 ± 0.2 | 2.9 ± 0.5 | 1.00 | 3.0 ± 0.1 | 1.03 | 2.2 ± 0.2 | 0.75 |
| Decorin | 14.0 ± 0.1 | 15.0 ± 0.3 | 1.07 | 11.2 ± 1.2 | 0.80 | 10.5 ± 0.1 | 0.80 |
| Fibronectin | 0.9 ± 2.8 | 0.5 ± 0.1 | 0.53 | 0.3 ± 1.2 | 0.33 | 0.49 ± 0.01 | 0.55 |
| Osteocalcin | 1.68 ± 0.1 | 0.72 ± 0.02 | 0.42 | 0.9 ± 1.2 | 0.53 | 1.0 ± 0.2 | 0.59 |
| Osteonectin | 2.5 ± 0.3 | 1.4 ± 0.2 | 0.55 | 2.5 ± 0.3 | 1.02 | 1.71 ± 0.02 | 0.69 |
| Osteopontin | 15.1 ± 0.3 | 9.0 ± 0.4 | 0.59 | 8.8 ± 1.1 | 0.58 | 4.5 ± 1.2 | 0.29 |
| Type-I collagen | 20.0 ± 1.0 | 17.5 ± 1.4 | 0.87 | 14.5 ± 1.9 | 0.72 | 12.7 ± 1.1 | 0.63 |
| Type-III collagen | 2.7 ± 0.1 | 3.7 ± 0.1 | 1.36 | 3.0 ± 0.2 | 1.09 | 1.90 ± 0.11 | 0.69 |