FIG. 1.

Changes in expression of energy-generating pathways of E. coli under anaerobic conditions. Changes in expression of fermentation pathways, TCA cycle, and electron transport systems from the global gene expression data are represented by the different color intensities of lines and protein names, where dark blue are the most anaerobically repressed functions and dark red are the most anaerobically activated functions. The three major branch points that determine the fluxes of carbon and electrons through the various pathways are labeled in bold and larger font. This figure is adapted from Spiro and Guest (82) and Alexeeva et al. (1). The direction of the triangles indicates whether the gene product is positively (Δ) or negatively (▿) regulated by FNR.