TABLE 3.
Genea | Gene product and/or functionb | Fold decrease | P value (<0.05) |
---|---|---|---|
Transport and binding | |||
actP | Acetate permease | 3.1 | 4.4 × 10−3 |
csgF | Possible assembly or transport protein for curli | 6.2 | 2.5 × 10−3 |
csgG | Possible assembly or transport protein for curli; novel lipoprotein | 2.7 | 4.3 × 10−4 |
gadC | Putative glutamate-γ-aminobutyrate antiporter. | 5.9 | 1.7 × 10−5 |
lsrB | Part of a system for autoinducer 2 uptake in Salmonella | 2.5 | 4.4 × 10−3 |
hdeD | Putative membrane transporter, H-NS repressed | 2.8 | 2.4 × 10−4 |
lsrD | Part of a system for autoinducer 2 uptake in Salmonella | 2.1 | 1.0 × 10−2 |
lsrG | Function unknown; part of an operon for autoinducer 2 uptake in Salmonella | 2.8 | 1.1 × 10−3 |
ompW | Outer membrane protein; colicin S4 receptor | 2.4 | 2.9 × 10−2 |
ugpA | sn-Glycerol-3-phosphate transport system; integral membrane protein | 2.2 | 3.5 × 10−2 |
ugpE | sn-Glycerol-3-P transport system | 2.4 | 5.0 × 10−3 |
uidB | Glucuronide permease | 3.7 | 8.1 × 10−3 |
ydcU | Function unknown; putative ABC transporter permease protein | 2.2 | 8.0 × 10−4 |
ygjU | Na+/serine (threonine) symporter | 2.3 | 6.0 × 10−4 |
Other gene implicated in responses to metals | |||
yrbL | Mg(II) starvation-stimulated gene; function unknown; phoPQ regulon | 7.7 | 3.0 × 10−7 |
Genes implicated in response to stresses other than metals | |||
csgD | Transcriptional regulator for curli operon csgBA | 2.3 | 2.0 × 10−3 |
csiE | Stationary-phase inducible protein; sigma S-dependent promoter | 2.7 | 5.0 × 10−4 |
cstA | Starvation-induced protein involved in peptide utilization during carbon starvation | 2.3 | 8.3 × 10−4 |
dps | Stress response DNA-binding protein | 2.1 | 1.3 × 10−3 |
gadE | Required for stationary-phase induction; pH 5.5 growth medium induced; overexpression confers acid resistance | 2.7 | 1.7 × 10−4 |
hdeB | Acid resistance; periplasmic protein; repressed by H-NS; rpoS regulon | 5.8 | 1.7 × 10−4 |
osmE | Regulated by growth phase as well as osmotic pressure | 2.9 | 3.5 × 10−4 |
osmC | Osmotically inducible, stress-inducible membrane protein C; involved in defense against oxidative compounds | 2.6 | 7.2 × 10−7 |
psiF | pho regulon member, requiring PhoRB system | 2.4 | 2.9 × 10−3 |
rssB | Two-component response regulator, affecting RpoS regulon | 2.2 | 3.6 × 10−2 |
sodC | Superoxide dismutase; Cu, Zn, periplasmic | 2.6 | 2.3 × 10−5 |
uspB | Ethanol resistance in stationary phase | 2.1 | 5.5 × 10−3 |
Periplasmic protein | |||
hdeA | Periplasmic chaperone of acid-denatured proteins | 5.4 | 3.6 × 10−5 |
Extracellular protein | |||
hlyE | Latent hemolysin | 2.9 | 2.0 × 10−2 |
Intermediary metabolism | |||
astA | Putative arginine succinyltransferase | 3.9 | 1.1 × 10−4 |
gadB | Glutamate decarboxylase B, vitamin B6 dependent | 5.3 | 3.7 × 10−6 |
otsB | Trehalose phosphate phosphatase; cold and heat induced | 2.3 | 5.6 × 10−3 |
talA | Transaldolase A; creBC regulon | 2.1 | 2.1 × 10−2 |
Membrane structure | |||
frdD | Fumarate reductase membrane anchor polypeptide | 2.0 | 3.5 × 10−3 |
ychH | Function unknown; putative membrane protein transcribed divergently from pth | 2.6 | 1.0 × 10−2 |
ynfA | Inner membrane protein; function unknown | 2.5 | 8.9 × 10−4 |
Phage-related function | |||
sgcC | Putative phosphotransferase enzyme IIC | 5.3 | 6.4 × 10−4 |
sgcX | Putative gene in sgc cluster; function unknown | 3.5 | 1.3 × 10−4 |
stfR | Phage lambda stf gene homolog in prophage Rac | 2.0 | 4.9 × 10−2 |
Unclassified | |||
elaB | Function unknown | 2.4 | 1.2 × 10−4 |
yagU | Function unknown | 5.1 | 4.5 × 10−5 |
yahO | Function unknown | 3.1 | 5.3 × 10−3 |
ybaY | Function unknown | 2.2 | 1.1 × 10−3 |
ycfH | Putative DNAse; tatD paralog; no Tat phenotype | 2.2 | 5.1 × 10−3 |
ycgK | Function unknown | 5.2 | 5.0 × 10−3 |
ydeI | Function unknown | 2.2 | 1.0 × 10−2 |
ydhZ | Function unknown | 2.7 | 4.8 × 102− |
yeaQ | Function unknown | 2.1 | 2.6 × 10−4 |
yebV | Function unknown | 2.4 | 1.2 × 10−3 |
yhcO | Function unknown | 2.5 | 3.5 × 10−2 |
yhfG | Function unknown | 2.4 | 1.9 × 10−4 |
yjbJ | Function unknown | 2.0 | 1.3 × 10−2 |
yjfO | Function unknown | 2.4 | 3.3 × 10−2 |
yoaE | Function unknown | 2.3 | 9.8 × 10−4 |
yodD | Function unknown | 2.1 | 4.9 × 10−3 |
ytfR | Function unknown | 2.4 | 4.2 × 10−4 |
ytfT | Function unknown | 3.0 | 3.7 × 10−2 |
ytfR | Function unknown | 2.4 | 4.2 × 10−4 |
ytfT | Function unknown | 3.0 | 3.7 × 10−2 |
Gene names obtained from http://bmb.med.miami.edu/EcoGene/EcoWeb/.
Gene product descriptions obtained from http://bmb.med.miami.edu/EcoGene/EcoWeb/.