TABLE 5.
Sequence motifs in the glutamate transporter family
| Motif | Sequence |
|---|---|
| B (all members) | 317a PxGx (TS) xN (ML) DbGxcx (LI) (FY) 330a |
| D | |
| Bacterial C4-dicarboxylate transporters | DRFMSExRxxxNxxGN |
| Bacterial glutamate transporters | DRxxDMARTxxNxxG (NH) |
| Eukaryotic Ala/Ser/Cys/Thr transporters | DWxVDRxxTxxNVEGD |
| Eukaryotic neutral amino acid transporters | DWxVDRxxTxxNVEGD |
| Eukaryotic glutamate transporters | DWxLDRxRTxxNVxGD |
| Third transmembrane domain | |
| Bacterial C4-dicarboxylate transporters | 99a AxxY---Fxxx(ST)TxA---LxxGdL 115b |
| Bacterial glutamate transporters | TII(YW)FExIT---TI----xxxGL |
| Eukaryotic Ala/Ser/Cys/Thr transporters | AVAY---FGLTT---LSA---SALAV |
| Eukaryotic neutral amino acid transporters | ALLF---FLVTT---LLA---SALGV |
| Eukaryotic glutamate transporters | AxxY---YxxTT---xxA---xxxG (IV) |
a
Position on S. meliloti DctA.
b
Position of mutation in pSM100-41 D325G.
c
Position of mutation in pSM100-53 T327A.
d
Position of mutation in pSM100-32 G114D.