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. 2017 May 30;9:1179299X17710944. doi: 10.1177/1179299X17710944

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Examples of fascin-1 and ETS-related gene (ERG) staining patterns in human prostate carcinomas from the tissue microarray. (A, B) Staining for fascin-1; (C, D), staining for ERG. (A) and (C) are from Gleason grade 6 tumours with fascin-1 (A) or ERG (C), staining that is indistinguishable from the normal tissue. (B) Example of a Gleason grade 8 tumour with elevated fascin-1 in the stroma and de-differentiated glands. Arrow indicates a predominantly fascin-1–negative gland adjacent to 2 fascin-1–positive glands. (D) Example of a Gleason grade 7 tumour with elevated nuclear ERG in most cells.