Table 4.
Multivariate analysis for 3-year OS and DSS for all patients
| Variables | Comparison | DSS
|
OS
|
||
|---|---|---|---|---|---|
| P-value | aHR (95% CI) | P-value | aHR (95% CI) | ||
| Sex | Female vs male | 0.154 | 1.721 (0.816–3.627) | 0.772 | 1.107 (0.557–2.197) |
| CCIS | ≥1 vs 0 | 0.278 | 1.574 (0.694–3.572) | 0.141 | 1.672 (0.843–3.318) |
| T classification | T3/T4 vs T1/T2 | 0.596 | 1.231 (0.571–2.651) | 0.547 | 1.226 (0.632–2.378) |
| N classification | N2/N3 vs N0/N1 | 0.245 | 1.928 (0.638–5.827) | 0.243 | 1.668 (0.706–3.938) |
| Treatment | CCRT vs RT | 0.870 | 1.107 (0.328–3.734) | 0.910 | 0.946 (0.360–2.483) |
| CCRT vs RT/CCRT + CT | 0.466 | 1.387 (0.575–3.342) | 0.683 | 0.861 (0.419–1.769) | |
| COP-NLR score | 1&2 vs 0 | 0.020 | 2.445 (1.148–5.206) | 0.024 | 2.106 (1.102–4.025) |
Abbreviations: DSS, disease-specific survival; OS, overall survival; aHR, adjusted hazard ratio; CI, confidence interval; CCIS, Charlson Comorbidity Index Score; CCRT, concurrent chemoradiotherapy; RT, radiotherapy; CT, chemotherapy; COP-NLR, combination of platelet count and neutrophil–lymphocyte ratio.