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Genomic Southern hybridization of temperature-resistant Cmr S. suis mutants. Genomic DNAs were digested with StuI, separated by agarose gel electrophoresis, and probed with labeled SsuDAT1I genes. Molecular sizes are indicated on the right. Lane numbers correspond to the numbers in the designations of mutants Int1 to Int12. W, wild-type strain 227; M, mutant strain 227catIN.
