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Indices of insulin resistance: Apparent HOMA-IR in GK and WKY rats with age. N = 5 animals per group. Symbols represent mean values and error bars 1 SD of the mean. No significant differences were apparent in HFD versus ND animals, but differences were significant between GK and WKY animals on either diet. ##P < .001. GK indicates Goto-Kakizaki; HFD, high-fat diet; ND, normal diet; WKY, Wistar-Kyoto.
