Table 2.
Cardiovascular mortality in patients with rheumatoid arthritis (RA) and subjects without RA by decade of incidence/index
| Incidence/index year | 1980–1989 | 1990–1999 | 2000–2007 | |||
|---|---|---|---|---|---|---|
|
| ||||||
| RA | Non-RA | RA | Non-RA | RA | Non-RA | |
| Number of patients | 202 | 202 | 296 | 296 | 315 | 315 |
| Median follow-up (IQR), years | 10.2 (7.8, 12.5) | 10.1 (7.4, 12.2) | 10.0 (7.4, 12.2) | 9.9 (7.0, 12.1) | 9.0 (7.3, 11.0) | 9.7 (7.9, 11.8) |
| CV deaths | 29 | 19 | 19 | 16 | 8 | 9 |
| - CHD deaths | 15 | 9 | 12 | 7 | 2 | 3 |
| - Non-CHD deaths | 5 | 2 | 5 | 6 | 2 | 2 |
| Unadjusted 10-year mortality, % | ||||||
| - CV mortality | 13.6±2.6 | 10.2±2.4 | 7.1±1.6 | 5.7±1.4 | 2.7±1.1 | 3.1±1.1 |
| - CHD mortality | 7.6±2.1 | 4.4±1.3 | 4.5±1.3 | 2.4±0.9 | 1.1±0.8 | 1.2±0.7 |
| - non-CHD | 1.9±1.1 | 1.5±1.1 | 1.9±0.8 | 2.2±0.9 | 0.7±0.5 | 0.9±0.7 |
| Age and sex adjusted 10-year mortality, % | ||||||
| - CV mortality | 12.4±2.4 | 8.9±2.2 | 6.9±1.6 | 5.3±1.3 | 3.1±1.2 | 3.5±1.3 |
| - CHD mortality | 6.8±1.9 | 4.0±1.4 | 4.3±1.3 | 2.2±0.8 | 1.1±0.8 | 1.4±0.8 |
| - non-CHD | 1.8±1.0 | 1.2±0.9 | 2.0±0.9 | 2.1±0.9 | 0.9±0.6 | 1.0±0.7 |
Abbreviations: RA = rheumatoid arthritis; CV = cardiovascular; CHD = coronary heart disease; IQR= interquartile range