Table 5.
Multivariable Model for Pediatric Cohort
| Characteristic | Outcome
|
|||
|---|---|---|---|---|
| Mortality
|
FSSa (among survivors)
|
|||
| Adjusted Relative Riskb (95% CI) | P-value | Adjusted Effectc (95% CI) | P-value | |
| Indication for ECMOd | <.01 | |||
| Respiratory | --- | ---- | Reference | |
| Cardiac | --- | --- | −0.89 (−1.85, 0.07) | |
| ECPRe | --- | --- | 1.41 (−0.09, 2.91) | |
| Neurologic chronic diagnosis | 1.82 (0.31, 3.33) | 0.02 | ||
| Chronic cardiovascular diagnosis | 1.33 (1.06, 1.67) | 0.01 | --- | |
| Other chronic diagnosis | --- | --- | 1.11 (0.04, 2.18) | 0.04 |
| Hepatic organ dysfunction | 1.39 (1.09, 1.76) | <.01 | 2.03 (0.96, 3.10) | <.01 |
| Baseline ventilator or tracheostomy | --- | --- | 11.67 (8.01, 15.33) | <.01 |
| ICU LOS (weeks)f | --- | --- | 0.08 (0.03, 0.13) | <.01 |
| Neurologic event | 1.82 (1.39, 2.37) | <.01 | --- | --- |
| Thrombotic event | 1.43 (1.13, 1.80) | <.01 | --- | --- |
| Achieved lactate < 2 mmol/L | 0.54 (0.43, 0.68) | <.01 | --- | --- |
FSS is Functional Status Score;
Mortality was modeled using Poisson regression with robust error estimates;
FSS among survivors was modeled using standard linear regression;
ECMO is extracorporeal membrane oxygenation;
ECPR is extracorporeal cardiopulmonary resuscitation;
LOS is length of stay