Table 4.
Effect of affected mother vs. father; effect of multiple affected parents; and effects of covariates.
| Predictor/Covariate | Unadjusted Model OR (95% CI) | Adjusted Model OR (95% CI) |
|---|---|---|
| EB in mother but not father | 2.67 (2.36, 2.99) | 2.49 (2.21, 2.80) |
| EB in father but not mother | 2.70 (2.52, 2.88)1 | 2.51 (2.34, 2.68)2 |
| EB in mother x EB in father (interaction term) | 0.60 (0.49, 0.72) | 0.60 (0.50, 0.72) |
| Males vs. females | 1.97 (1.81, 2.14) | |
| Cohort 1975–1979 vs. 1970–1974, females | 0.97 (0.87, 1.07) | |
| Cohort 1980–1984 vs. 1970–1974, females | 1.21 (1.10, 1.34) | |
| Cohort 1975–1979 vs. 1970–1974, males | 0.72 (0.67, 0.78) | |
| Cohort 1980–1984 vs. 1970–1974, males | 0.72 (0.66, 0.78) | |
| Parental education (high vs. low) | 0.63 (0.58, 0.68) | |
| Parental education (mid vs. low) | 0.94 (0.87, 1.01) |
In the unadjusted model, the OR for having both parents affected is 4.30.
In the adjusted model, the OR for having both parents affected is 3.77.