Table 2.
Performance characteristics of non-contrast MRI images with HASTE versus contrast-enhanced MRI/3D-MRCP in patients with suspected acute cholestasis. P values are from McNemar tests to compare image sets in terms of accuracy, sensitivity and specificity or from GEE to compare the sets in terms of predictive values.
| Abbreviated Image Set | Contrast-MRI/MRCP | P Value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcome | Component | Reader | % Correct | # Correct | N | % Correct | # Correct | N | |
| Choledocholithiasis | Accuracy | 1 | 94.3% | 116 | 123 | 92.7% | 114 | 123 | 0.797 |
| Accuracy | 2 | 91.1% | 112 | 123 | 91.9% | 113 | 123 | 1.000 | |
| NPV | 1 | 95.9% | 93 | 97 | 94.8% | 92 | 97 | 1.000 | |
| NPV | 2 | 91.3% | 94 | 103 | 92.2% | 94 | 102 | 1.000 | |
| PPV | 1 | 88.5% | 23 | 26 | 84.6% | 22 | 26 | 1.000 | |
| PPV | 2 | 90.0% | 18 | 20 | 90.5% | 19 | 21 | 1.000 | |
| Sensitivity | 1 | 85.2% | 23 | 27 | 81.5% | 22 | 27 | 1.000 | |
| Sensitivity | 2 | 70.0% | 18 | 27 | 70.4% | 19 | 27 | 1.000 | |
| Specificity | 1 | 96.9% | 93 | 96 | 95.8% | 92 | 96 | 1.000 | |
| Specificity | 2 | 97.9% | 94 | 96 | 97.9% | 94 | 96 | 1.000 | |
| Alternative Diagnosis in Biliary Tree | Accuracy | 1 | 82.9% | 102 | 123 | 78.0% | 96 | 123 | 0.421 |
| Accuracy | 2 | 82.8% | 101 | 122 | 83.6% | 102 | 122 | 1.000 | |
| NPV | 1 | 86.9% | 93 | 107 | 84.8% | 89 | 105 | 0.697 | |
| NPV | 2 | 85.5% | 94 | 110 | 86.2% | 94 | 109 | 1.000 | |
| PPV | 1 | 56.3% | 9 | 16 | 38.9% | 7 | 18 | 0.492 | |
| PPV | 2 | 58.3% | 7 | 12 | 61.5% | 8 | 13 | 1.000 | |
| Sensitivity | 1 | 39.1% | 9 | 23 | 30.4% | 7 | 23 | 0.758 | |
| Sensitivity | 2 | 30.4% | 7 | 23 | 34.8% | 8 | 23 | 1.000 | |
| Specificity | 1 | 93.0% | 93 | 100 | 89.0% | 89 | 100 | 0.459 | |
| Specificity | 2 | 94.9% | 94 | 99 | 94.9% | 94 | 99 | 1.000 | |
| Acute Hepatitis | Accuracy | 1 | 76.4% | 94 | 123 | 76.4% | 94 | 123 | 1.000 |
| Accuracy | 2 | 78.9% | 97 | 123 | 78.0% | 96 | 123 | 1.000 | |
| NPV | 1 | 77.4% | 89 | 115 | 77.9% | 88 | 113 | 1.000 | |
| NPV | 2 | 78.0% | 92 | 118 | 77.8% | 91 | 117 | 1.000 | |
| PPV | 1 | 62.5% | 5 | 8 | 60.0% | 6 | 10 | 1.000 | |
| PPV | 2 | 100% | 5 | 5 | 83.3% | 5 | 6 | 1.000 | |
| Sensitivity | 1 | 16.1% | 5 | 31 | 19.4% | 6 | 31 | 1.000 | |
| Sensitivity | 2 | 16.1% | 5 | 31 | 16.1% | 5 | 31 | 1.000 | |
| Specificity | 1 | 96.7% | 89 | 92 | 95.7% | 88 | 92 | 1.000 | |
| Specificity | 2 | 100% | 92 | 92 | 98.9% | 91 | 92 | 1.000 | |
| Ascending Cholangitis | Accuracy | 1 | 96.7% | 119 | 123 | 97.6% | 120 | 123 | 1.000 |
| Accuracy | 2 | 98.4% | 121 | 123 | 98.4% | 121 | 123 | 1.000 | |
| NPV | 1 | 98.3% | 118 | 120 | 99.2% | 118 | 119 | 1.000 | |
| NPV | 2 | 98.4% | 120 | 122 | 99.2% | 119 | 120 | 1.000 | |
| PPV | 1 | 33.3% | 1 | 3 | 50.0% | 2 | 4 | 1.000 | |
| PPV | 2 | 100% | 1 | 1 | 66.7% | 2 | 3 | 1.000 | |
| Sensitivity | 1 | 33.3% | 1 | 3 | 66.7% | 2 | 3 | 1.000 | |
| Sensitivity | 2 | 33.3% | 1 | 3 | 66.7% | 2 | 3 | 1.000 | |
| Specificity | 1 | 98.3% | 118 | 120 | 98.3% | 118 | 120 | 1.000 | |
| Specificity | 2 | 100% | 120 | 120 | 99.2% | 119 | 120 | 1.000 | |