Table 4.
Obesity and Breast Cancer Risk by Tumor Type, Multiethnic Cohort, 1993-2010a
| Ethnicity | ER/PR status | Cases with T2D | HR | 95% CI |
|---|---|---|---|---|
| White | ER+/PR+ | 885 | 1.36 | 1.12, 1.66 |
| ER−/PR− | 195 | 1.03 | 0.67, 1.58 | |
| Discordant | 179 | 1.03 | 0.64, 1.66 | |
| African American | ER+/PR+ | 453 | 1.53 | 1.17, 2.00 |
| ER−/PR− | 209 | 1.00 | 0.68, 1.46 | |
| Discordant | 134 | 0.89 | 0.56, 1.42 | |
| Native Hawaiian | ER+/PR+ | 391 | 1.52 | 1.15, 2.01 |
| ER−/PR− | 74 | 0.89 | 0.49, 1.63 | |
| Discordant | 59 | 1.38 | 0.69, 2.76 | |
| Japanese American | ER+/PR+ | 1123 | 1.71 | 1.37, 2.12 |
| ER−/PR− | 226 | 1.19 | 0.68, 2.08 | |
| Discordant | 247 | 0.97 | 0.57, 1.66 | |
| Latina | ER+/PR+ | 439 | 1.34 | 1.04, 1.74 |
| ER−/PR− | 177 | 0.88 | 0.58, 1.35 | |
| Discordant | 109 | 1.06 | 0.64, 1.77 | |
| US-born | ER+/PR+ | 259 | 1.35 | 0.97, 1.89 |
| ER−/PR− | 92 | 1.16 | 0.66, 2.03 | |
| Discordant | 69 | 1.06 | 0.55, 2.04 | |
| Foreign-born | ER+/PR+ | 180 | 1.25 | 0.83, 1.89 |
| ER−/PR− | 65 | 0.56 | 0.28, 1.11 | |
| Discordant | 40 | 0.87 | 0.36, 2.06 |
a
Hazard ratios (HR) and 95% confidence intervals (CI) for obese (>30 kg/m2) vs. normal weight (20-<25 kg/m2) obtained by Cox regression with age as time metric and adjusted for age at cohort entry, education, family history of breast cancer, alcohol intake, physical activity, age at menarche, parity, age at first live birth, postmenopausal hormone use, and T2D.