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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Pain. 2017 Feb 7;18(6):687–701. doi: 10.1016/j.jpain.2017.01.006

FIGURE 3. Voluntary exercise prevents CFA-induced reductions in heart rate variability.

FIGURE 3

(A/B) Neither heart rate nor R-R interval were significantly changed by CFA or access to running wheels. (C) However, a significant decrease in SDNN for the CFA-SED group along with a trend toward increased SDNN for the sham group were found. (D) Similarly, a trend toward a decrease in RMSSD for the CFA-SED group along with a significant increase in SDNN for the sham group were found. Delta scores for SDNN and RMSSD showed that CFA-induced decreases in both SDNN (E) and RMSSD (F) were mitigated in the CFA-RUN group. Stars (*) signify significant comparisons with sham group. */p<0.05, n=16–34.