Table 3.

Correlation Estimates for the RP Data Set (220 patients, 440 eyes)^*

		Crude				Adjusted
Type of correlation	Parameter	Point estimate	95% CI	P-value	Neyes (Neyes,obs**)	Point estimate	95% CI	P-value	Neyes (Neyes,obs**)
Pearson	ρxy	0.212	(0.088, 0.329)	<0.001	440 (433)	0.195	(0.071, 0.312)	0.002	440 (433)
	${\mathrm{\rho }}_{\text{xy}}^{\ast }$	0.177	(0.054, 0.295)	0.004	440 (433)	0.156	(0.033, 0.274)	0.012	440 (433)
	ρxx	0.787				0.766
	${\mathrm{\sigma }}_{\mathrm{x}}^2$	100.2				91.1
	ρyy	0.944				0.943
	${\mathrm{\sigma }}_{\mathrm{y}}^2$	227, 330				201, 710
Rank	ρxy,s	0.229	(0.110, 0.341)	<0.001	440 (433)	0.221	(0.103, 0.333)	<0.001	440 (433)
	${\mathrm{\rho }}_{\text{xy},\mathrm{s}}^{\ast }$	0.200	(0.082, 0.312)	<0.001	440 (433)	0.189	(0.072, 0.301)	0.001	440 (433)
	ρxx,s	0.819				0.807
	${\mathrm{\sigma }}_{\mathrm{x},\mathrm{s}}^2$	0.946				0.891
	ρyy,s	0.909				0.900
	${\mathrm{\sigma }}_{\mathrm{y},\mathrm{s}}^2$	0.962				0.884

^*VA is available for 219 patients for the right eye (OD) and 216 patients for the left eye (OS); VF is available for 217 patients for the right eye (OD) and 216 patients for the left eye (OS); age, gender and genetic type are available for all 220 patients; missing data are accounted for using multiple imputation.

^**N_eyes,obs = number of eyes where both VA and VF are observed; N_eyes = number of eyes observed + number of eyes imputed for the characteristic

computer run:

• :/proj/stross/stros0a/rankcorrelation/correlation.ranked.proc.mi3a.sas 11/23/15
• :/proj.stross/stros0a/rankcorrelation/correlation.ranked.proc.mi.residual.probit.sas 12/04/15
• :/proj/stross/stros0a/rankcorrelation/correlation.ranked.proc.mi.residual.sas 12/04/15