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. 2017 Jun 2;7:2701. doi: 10.1038/s41598-017-02953-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Maximum likelihood tree and associated function of the aminergic toxins from MT3-MT1 evolutionary pathway. Bootstraps value higher than 50% are shown. Toxin’s functions are illustrated by circles identifying the receptor targeted (color) and the corresponding K_i value (circle size), as described in the right legend, at the right side of each toxin name.