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. 2017 Jun 2;7:2715. doi: 10.1038/s41598-017-02996-3

Table 1.

Minimal inhibitory concentration (MIC)50/90 and minimal bactericidal concentration (MBC)50/90 values of Rhodomyrtus tomentosa ethanol extract, purified rhodomyrtone, and synthetic rhodomyrtone against Streptococcus pneumoniae clinical isolates.

Antibacterial agents Antibacterial activity (µg/ml)
S. pneumoniae clinical isolates S. pneumoniae ATCC 700673
MIC50/MBC50 MIC90/MBC90 MIC range MBC range MIC/MBC
Ethanol extract 64/128 128/512 16–256 16–512 32/128
Purified rhodomyrtone 0.50/1 2/4 0.125–4 0.125–4 0.50/1
Synthetic rhodomyrtone 0.50/2 2/4 0.125–4 0.25–4 1/4
Erythromycin 0.03/0.03 0.25/0.50 0.03–2 0.03–4 0.125/0.25