Figure 1.

Wnt/β-catenin signaling pathway was deleted or activated in different levels at fracture sites in WT, β-catenin-KO, CA-β-catenin and SA-β-catenin mice. The mRNA expression level of β-catenin, TCF and LEF1 were examined by RT-PCR (A–C). The values are expressed as the means ± SDs. (n = 6/group, *p < 0.05, **p < 0.01).