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. 2017 Jun 2;7:2705. doi: 10.1038/s41598-017-02881-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of resveratrol on apoptotic cell death in the livers of aged mice treated with Con A. (a) Protein lysates were analyzed using Western blotting with the antibodies against Bcl-2, Bax and cytochrome C (cyt C). Data are means ± SEMs from three independent measurements. (b) TUNEL staining with FITC fluorescein label. DAPI is the nuclear stain. The images are shown at 200 × magnification, with the upper right grid at 400 × enlargement for selected squares. The length of scale bar was indicated as 200 μm. (c and d) The hepatic activity of caspase 3 and caspase 8 (n = 7 in each group). Different letters denote statistically significant differences (p < 0.05) between groups.