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. 2017 May 23;8:15466. doi: 10.1038/ncomms15466

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Regional association plot for LOXL1 gene with 100 kb upstream and downstream regions shows the association peak region for SNPs located on the LOXL1 gene locus. Association analysis was performed using a logistic regression model adjusted for age and gender. The data of all SNPs are indicated as circles. The red and orange circles represent the 14 SNPs showing major association. The left Y-axis represents –log₁₀ P values and the right Y axis represents the recombination rate. The X axis represents position of SNPs on chromosome 15 (human genome build GRCh37/hg19).