Table 2.
Effects of the SL extract on body lipid accumulation and serum components in mice
| ND group | HFD group | SL extract group | |
|---|---|---|---|
| Final body weight, g | 25.5 ± 1.0b | 33.4 ± 1.0 | 33.5 ± 1.8 |
| 4 week total food intake, g/mouse | 85.8 | 119.6 | 125.3 |
| 8 week total food intake, g/mouse | 159.5 | 204.7 | 216.6 |
| Liver, g/100 g body weight | 3.56 ± 0.12 | 3.69 ± 0.09 | 3.16 ± 0.19a |
| Epididymal WAT, g/100 g body weight | 3.01 ± 0.15c | 6.78 ± 0.56 | 6.22 ± 0.43 |
| Serum glucose, mg/dL | 43.0 ± 4.2c | 173.0 ± 10.9 | 140.8 ± 2.6a |
| Serum Insulin, ng/mL | 0.29 ± 0.07b | 0.93 ± 0.14 | 0.46 ± 0.07a |
| HOMA-IR | 0.33 ± 0.09b | 2.14 ± 0.35 | 0.85 ± 0.13b |
| Serum glycoalbumin, % | 3.7 ± 0.1c | 4.5 ± 0.1 | 4.1 ± 0.1b |
| Serum T-CHO, mg/dL | 77.0 ± 5.5c | 169.8 ± 6.3 | 141.0 ± 4.7b |
| Serum TG, mg/dL | 69.5 ± 8.7a | 45.1 ± 7.6 | 39.8 ± 2.9 |
| Serum FFA, mEq/L | 1.03 ± 0.02b | 0.82 ± 0.06 | 0.79 ± 0.03 |
| Serum ketone bodies, mmol/L | 2.03 ± 0.01 | 2.40 ± 0.14 | 3.18 ± 0.23b |
| Serum ALT, IU/L | 17.5 ± 1.2c | 87.1 ± 10.8 | 31.9 ± 5.9c |
| Serum AST, IU/L | 49.5 ± 1.7c | 146.6 ± 13.9 | 79.0 ± 8.3c |
Data are expressed as the mean ± SEM of five mice (ND group), nine mice (HFD group and nine mice (SL extract group) except total food intake. Statistically significant differences between groups were determined using ANOVA; a p < 0.05,b p < 0.01,c p < 0.001 vs. the HFD group