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. 2017 Jun 3;17:401. doi: 10.1186/s12885-017-3386-2
Drug Dose Administration Days Given
Epirubicin 50 mg/m2 Slow IV push into the side arm of NaCl 0.9% drip Day 1
Cisplatin with hydration - mannitol 10%* 60 mg/m2 Dilute in NaCl 0.9%.
500 mls Administer over 2 h.
OR Infuse concurrently with cisplatin over 2 h Day 1
Oxaliplatin 130 mg/m2 Dilute in Dextrose 5%.
Administer over 2 h
5-Fluorouracil 200 mg/m2/d Given at a dose of 200 mg/m2/day by continuous infusion every day for 21 days/3 weeks Daily for 21 days/3 weeks
OR
Capecitabine 625 mg/m2 twice daily Taken orally twice daily for 21 days Daily for 21 days/3 weeks