| Drug | Dose | Administration | Days Given |
|---|---|---|---|
| Epirubicin | 50 mg/m2 | Slow IV push into the side arm of NaCl 0.9% drip | Day 1 |
| Cisplatin with hydration - mannitol 10%* | 60 mg/m2 | Dilute in NaCl 0.9%. | |
| 500 mls | Administer over 2 h. | ||
| OR | Infuse concurrently with cisplatin over 2 h | Day 1 | |
| Oxaliplatin | 130 mg/m2 | Dilute in Dextrose 5%. Administer over 2 h |
|
| 5-Fluorouracil | 200 mg/m2/d | Given at a dose of 200 mg/m2/day by continuous infusion every day for 21 days/3 weeks | Daily for 21 days/3 weeks |
| OR | |||
| Capecitabine | 625 mg/m2 twice daily | Taken orally twice daily for 21 days | Daily for 21 days/3 weeks |