Table 1.
Demographic characteristics of the SSc patients in the three cohorts at the baseline visit.
| Demographic characteristics | CSRG | ASCS | GENISOS | Total |
|---|---|---|---|---|
| (n=714) | (n=493) | (n=299) | n=1506 | |
| Female gender, n (%) | 615(86.1) | 429(87) | 248 (82.9) | 1292(85.8) |
| Ethnicity, n (%) | ||||
| White | 644(90.2) | 464(94.1) | 141(47.2) | 1249(82.9) |
| African descent | 10(1.4) | 0 | 61(20.4) | 71(4.7) |
| Latino | 3(0.4) | 1(0.2) | 86(28.8) | 90(6) |
| Asian | 17(2.4) | 20(4.1) | 10(3.3) | 47(3.1) |
| Native North American | 38(5.3) | 0 | 1(0.3) | 39(2.6) |
| Australian Aboriginal | 0 | 8(1.6) | 0 | 8(1.6) |
| Other | 2(0.3) | 0 | 0 | 2(0.1) |
| Diffuse involvement, n(%) | 286(40.1) | 127(26.7) | 175(58.5) | 588(39.5) |
| Age at enrollment, years, mean (±SD) | 55.6(12.1) | 57.8(12.4) | 48.7(12.8) | 54.9(12.8) |
| Disease duration, years, mean (±SD) | 10.7(9.0) | 11.9(10.0) | 2.5(1.6) | 9.5(9.2) |
| Anti-Scl 70, n (%) | 128(17.9) | 93(18.9) | 45(15) | 266(17.7) |
| Anti-Centromere B, n (%) | 248(34.7) | 42(14.1) | 200(40.8) | 490(32.6) |
| Anti-RNA polymerase III, n (%) | 126 (17.6) | 62 (12.6) | 41 (13.7) | 229 (15.2) |
| Th/To, n (%) | 10 (1.4) | 9 (1.8) | 5 (1.7) | 24 (1.6) |