Table 4.
Predictive significance of AFA for mortality in the multivariable model
| Variable | HR | 95% CI | p-value |
|---|---|---|---|
| Anti-fibrillarin positivity | 1.88 | 1.19, 2.97 | 0.007 |
| Female gender | 0.49 | 0.35, 0.68 | <0.001 |
| Ethnicity | |||
| White | 1 | 1, 1 | 1 |
| African descent | 2.05 | 1.25, 3.36 | 0.005 |
| Latino | 1.34 | 0.81, 2.22 | 0.26 |
| Asian | 1.15 | 0.54, 2.47 | 0.717 |
| Native North American | 1.04 | 0.50, 2.16 | 0.924 |
| Australian Aboriginal* | 15.78 | 2.15, 115.58 | 0.007 |
| Age at enrollment, years | 1.02 | 1.01, 1.04 | <0.001 |
| Site | |||
| GENISOS | 2.6 | 1.78, 3.8 | <0.001 |
| ASCS | 1.27 | 0.60, 2.66 | 0.534 |
AFA: Anti-fibrillarin antibodies.
*
No AFA positive patients in this ethnic group