Table 4. Virus titers in nasal wash fluids of ferrets in aerosol transmission experiment nasally inoculated with influenza A(H6N6) virus.
| Virus and time (DPI or DPE) of nasal wash fluid collectiona | Mean virus titer (log10EID50/mL)b | ||
|---|---|---|---|
| rgH6N6-222V/228S | |||
| 2 | ND | ND | ND |
| 4 | ND | ND | ND |
| 6 | 1.00 | ND | ND |
| 8 | 1.00 | ND | ND |
| rgH6N6 × pdm09-222V/228S | |||
| 2 | ND | 1.00 | ND |
| 4 | ND | ND | ND |
| 6 | ND | ND | ND |
| 8 | ND | ND | ND |
Abbreviations: day post exposure, DPE; day post inoculation, DPI; egg infectious dose, EID; not detected, ND.
a
Data are for virus inoculated ferrets and direct- and aerosol-contact exposure ferrets at various DPI or DPE.
b
Virus titers were determined by 50% egg infectious dose (EID50) in embryonated chicken eggs. The titers were generated from nasal swabs collected from three individual ferrets.