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. 2017 Mar 20;38(5):710–718. doi: 10.1038/aps.2016.161

Figure 2.

Figure 2

Species cross-reactivity of JS-001 and its affinity to PD-1 molecules in humans and cynomolgus monkeys. (A) An ELISA assay was used to determine the species cross-reactivity of JS-001 with antigens derived from different species. FCA analysis confirmed the affinity of JS-001 and PD-1 molecules to human and cynomolgus monkey PBMCs. (B) JS-001 binds to the PD-1 molecules on human PBMCs and (C) cynomolgus monkey PBMCs (CD4+ and CD8+ T cells). Data are given as the mean±SD from 3 independently analyzed experiments.