Skip to main content
. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2017 Mar 6;16(6):1114–1123. doi: 10.1158/1535-7163.MCT-16-0541

Figure 1. Schematic of Dosing Experiments.

Figure 1

Single dose effects were assessed by administering a dose of EPHARNA and groups of mice underwent necropsy at days +1, +14, or day +28 from EPHARNA dosing. To assess continuous dosing of EPHARNA, groups of mice were given EPHARNA twice weekly and underwent necropsy after 4 weeks of treatment. Non-human primates were given EPHARNA twice weekly for 9 administrations and underwent necropsy 43–45 days after the initial dosing.