TABLE III.
Associations between mouse allergen exposure and severity score and treatment step, among mouse sensitized
| CASI score β (95% CI) P value |
Treatment step β (95% CI) P value |
Prebronchodilator FEV1/FVC 85% OR (95% CI) P value |
Post-FEV1/FVC <85%*
OR (95% CI) P value |
|||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||
| Mus m 1 | Crude | Adjusted† | Crude | Adjusted† | Crude | Adjusted† | Crude | Adjusted† |
| log10(bed) |
0.60 (0.13 to 1.06)
P = .01 |
0.29 (−0.19 to 0.77)
P = 2A |
0.28 (0.08 to 0.49)
P = .006 |
0.22 (0.01 to 0.43)
P = .04 |
1.01 (0.76 to 1.35) P = .92 |
1.11 (0.81 to 1.53) P = .50 |
1.09 (0.77 to 1.56) P = .62 |
0.99 (0.67 to 1.48) P = .98 |
|
| ||||||||
| log10(bedroom floor) |
0.48 (0.10 to 0.86)
P = .01 |
0.43 (0.05 to 0.81)
P = .03 |
0.29 (0.12 to 0.45)
P = .001 |
0.26 (0.09 to 0.43)
P = .002 |
0.86 (0.69 to 1.09) P = .21 |
0.98 (0.76 to 1.26) P = .87 |
0.84 (0.63 to 1.14) P = .26 |
0.86 (0.62 to 1.21) P = .39 |
*
Restricted to participants 8 y and older because Hankinson equations are valid down to 8 y. n = 223-229 for log10(bed) and n = 197-202 for log10(bedroom floor).
†
Adjusted for age, sex, insurance, site, atopy (number of positive skin test results excluding mouse), race, Hispanic ethnicity, and mouse-specific IgE. n = 358-384 for log10(bed) and n = 325-349 for log10(be droom floor).