FIG. 10. Schematic of Tf-IR780 nanoparticle preparation, in vitro phototherapy, and biodistribution mediated by Tf-IR780 NPs. (A) Transferrin self-assembly with IR-780 with the help of dithiothreitol (DTT) to form Tf-IR780 NPs (B) Fluorescence images of CT-26 cells expressing singlet oxygen indicated by H2DCFDA staining for detection under photoirradiation (1 W/cm2; 808 nm) for 5 min (Scale bar=20µm). (C) In vivo fluorescence imaging in mice bearing CT-26 tumors administered with Tf-IR780 NPs (0.3 mg/kg, IR780). Figure images and accompanying legend are reproduced from (68). Copyright © 2017 Macmillan Publishers Limited.
