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. 2017 May 24;8:15159. doi: 10.1038/ncomms15159

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(a) Parasitemia in peripheral blood of NSG mice infected with the P. falciparum strain 3D7^0087/N9 (n=2 mice treated with vehicle and n=6 mice treated with E209). (b) Blood levels of E209 in the efficacy experiment shown in a over the first 24 h post-dosing. (c) dose/exposure–response relationship.