Study	Reason for exclusion
Alejandria 2012	Meta‐analysis from an International Congress on Infectious Diseases (ICID) poster abstract
Bakr 2011	4 different types of Widal Test used, that is, not a new rapid diagnostic test (RDT)
Banchuin 1987	Antigen detection was neither a commercially‐available rapid diagnostic test or a prototype.
Banerjee 1984	We were unable to extract specificity and sensitivity data
Boomsma 1988	We were unable to extract sensitivity and specificity data
Cardona‐Castro 2000	Not a commercially available test ('Dot Blot' Test from Bio‐Rad Laboratories, Richmond, CA)
Castonguay‐Vanier 2013	We could only extract data for patients with Gram‐negative rod positive blood cultures. The study authors did not present data on RDT performance on culture negative patients, therefore we could not perform analyses.
Chaicumpa 1992	Not a commercially available test (an unspecified Indirect dot blot ELISA)
Chart 2007	Not a commercially available RDT. A range of Salmonella serodiagnostic tests were performed at a UK reference laboratory on sera from UK residents returning from travelling abroad.
Chatterjee 1988	Not a commercially available test. "COAG" co‐agglutination test produced in‐house by Indian tertiary hospital laboratory.
Choo 1994	We were unable to extract data about performance of test in blood culture positive patients. DOT EIA (early Typhidot‐M).
Choo 1997	We were unable to extract relevant sensitivity and specificity data. DOT‐EIA (early Typhidot‐M).
Chua 2012	Evaluates a test for detecting chronic carriage rather than acute typhoid (enteric) fever
Coovadia 1986	Not a commercially available test (passive haemagglutination).
Das 2013	Not a commercially available test ‐ candidate created by SPAN Diagnostics (India)
Dhanalakshmi 1986	We were unable to determine which blood culture positive patients were also positive on the urinary COAG tests.
el‐Falaky 1970	We were unable to extract sensitivity and specificity data as no cut‐offs mentioned for haemagglutination.
Fadeel 2004	Not a commercial test: ELISA antibody detection from urine
Felezsko 2004	Letter outlining use of TUBEX to detect non‐typoidal Salmonella infections (e.g. S. enteritidis)
Gorelov 1988	Comparison of two types of Widal Test
Handojo 2004	Evaluation of a Widal slide agglutination test, a variant of an existing diagnostic test.
Hoffman 1986	Evaluation of a slide agglutination Widal Test
House 2005	Paired serum samples rather than a single use RDT
Jackson 1995	Dot Enzyme Immmunoassay (EIA) ‐ early Typhidot‐M. We were unable to extract sensitivity or specificity data.
John 1984	Not a commercial test: passive bacterial agglutination
Kalhan 1998	Not a commercial test: reverse passive haemagglutination assay (possible RDT candidate)
Kalhan 1999	Not a commercial test: Latex Agglutination Test
Kariuki 2004	No actual RDT evaluated. Study compared blood culture with the Widal Test.
Kaur 1988a	Not commercially‐available rapid diagnostic tests. In‐house latex agglutination (LAT) and coagglutination (COAG) tests which are not prototypes.
Kaur 1988b	The serodiagnostic tests evaluated were not commercially available point‐of‐care tests.
Khanam 2013	The TPTest is not a commercially‐available RDT
Khanam 2015	The study detailed the assessment of the human immune response rather than diagnostic test accuracy
Kollaritsch 1988	Letter to the editor about a single case ‐ not a diagnostic study
Korbsrisate 1998	Not a commercial test: Indirect ELISA IgM antibody detection
Kuchuloria 2016	No commercial RDTs were used in the febrile illness study, only laboratory serology for Salmonella Typhi
Lim 1998	Reference standard inadequately described, and not all patients received any form of reference standard. TUBEX.
Lutterloh 2012	Use of TUBEX to determine cases as part of active surveillance during an outbreak. We were unable to extract any data regarding diagnostic test accuracy.
Malik 2001	No data of index test (Typhidot) positivity in non‐culture positive patients.
Mukherjee 1993	Not a commercial test. In‐house co‐agglutination test
Munir 2015	This study only included clinical typhoid or conifrmed typhoid cases. Study authors excluded patients currently receiving or who had recently received antimicrobials. We were unable to extract data related to diagnostic test accuracy.
Narayanappa 2010	We were unable to extract data index test data (Typhidot‐M) from control (non‐typhoid fever) group
Neil 2012	Variety of serological diagnostic tests used during investigation of an acute outbreak in Uganda. No specific RDT used.
Nguyen 1997	The monoclonal antibody‐based dot‐blot ELISA evaluated is not a commercially‐available rapid diagnostic test.
Ong 1989	Test based on adherence IgM "capture" ‐ not commercially available. Confirmed typhoid case was blood or stool culture positive, or both.
Pandya 1995	Not a commercially available RDT: latex agglutination to a) Typhi Vi; and b) Barber protein
Petchclai 1987	Not a commercial test: passive haemagglutination test (PHA) We were unable to extract sensitivity and specificity data
Peterson 2010	Evaluation of general bacterial microarray/genetics rather than point‐of‐care testing
Preechakasedkit 2012	RDT development rather than evaluation of test accuracy
Rai 1989	Non‐commercial tests. We were unable to extract sensitivity and specificity data.
Shrivastava 2011	Repeat publication of data published by Olsen 2004 from Vietnam.
Surachmanto 2011	TUBEX in asthmatics. We were unable to extract diagnostic test data.
Tantivanich 1984	Not a commercial test: latex agglutination.
Thevanesam 1992	Widal Test evaluation, not a commercial RDT
Watt 2005	We were unable to extract sensitivity and specificity data
West 1989	Not a commercial test: urinary co‐agglutination technique
Wijedoru 2012	Data from this study had already been included in Moore 2014
Yan 2011	We were unable to extract specificity data
Zaka‐ur‐Rab 2012	Not a commercial test: Salivary IgA to lipopolysaccharide (LPS)

Abbreviations: RDT: rapid diagnostic test.