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. 2017 May 24;8:15655. doi: 10.1038/ncomms15655

Figure 2. Mechanisms of synthetic amide-forming reactions involving S-to-N acyl transfer.

Figure 2

(a) Native Chemical Ligation (NCL) (b) Ligation-desulfurization (c) Auxiliary-mediated ligation (AML) (d) Sequential NCL applied to chemical protein synthesis.