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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Nat Chem. 2017 Mar 6;9(4):325–332. doi: 10.1038/nchem.2739

Figure 5. Ribozyme-catalyzed RNA synthesis in phospholipid protocells.

Figure 5

a, Fluorescence micrograph of POPC vesicles containing RNA and NTPs, forming across a range of conditions with and without Mg2+ and K10 peptide; the membrane is stained with Rhodamine G (red) and encapsulated RNA is labeled with fluorescein (blue). b, PAGE of extensions at 17°C upon the long repeat template I-6 encapsulated within POPC vesicles, by tC9-4M added externally or within the vesicles. Quantification (N=4) of extension per primer and full-length extension are displayed beneath.