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. 2017 Feb 16;8(19):30766–30780. doi: 10.18632/oncotarget.15403

Figure 5. STAP2 has no capacity for memory CD8+ T cell differentiation in the LN.

Figure 5

Splenocytes derived from DUC18 mice were stimulated with mERK2 peptide for 3 days, transduced with STAP2-specific or scrambled control siRNA by electroporation, and then infused into BALB/c mice. At 4 or 44 days after infusion, these cells were collected from LNs and examined for the number of IFN-γ+ T cells, expression of memory markers (KLRG and IL-7R), and IFN-γ and TNF-α production by flow cytometry. (Gray filled; scrambled siRNA, Red line; STAP2 siRNA, black line; non-immunized control). The results are representative of two to four experiments. Data are expressed as the mean ± SD. *p < 0.05 is considered significant. n.s. = not significant.