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. 2017 Mar 9;8(19):30956–30970. doi: 10.18632/oncotarget.16042

Figure 4. Western blot in vivo experiments.

Figure 4

Ketamine administered during the second trimester perturbed NGF and down-regulated ERK, p-ERK, MSK, CREB, p-CREB, SYP, SYN, and PSD95 in the hippocampi of offspring. On postnatal day 30, after behavioral tests, brains were harvested for western blot analyses to determine the expression of NGF, ERK, p-ERK, MSK, CREB, p-CREB, SYP, SYN, and PSD95. (A–I) Above are representative immunoblots for the expression levels of the corresponding proteins, and below are the histograms of the quantification of the corresponding proteins normalized to GAPDH. Data are expressed as mean percentage ± SEM of control mean values. *p < 0.05.