Table 3. Association between TLR5 gene polymorphisms and risk of GC.

Genotype	Cases	Controls	OR (95% CI)*	P value
rs5744174
TT	794	858	1.00 (reference)
TC	425	390	1.18 (1.00–1.39)	0.047
CC	81	52	1.68 (1.18–2.41)	0.004
T			1.00 (reference)
C			1.24 (1.09–1.42)	0.001
rs5744140
CC	1069	1098	1.00 (reference)
CT	212	189	1.15 (0.93–1.43)	0.193
TT	19	13	1.50 (0.74–3.04)	0.259
C			1.00 (reference)
T			1.18 (0.97–1.43)	0.089
rs5744113
AA	768	772	1.00 (reference)
AG	440	448	0.99 (0.84–1.16)	0.879
GG	92	80	1.15 (0.84–1.58)	0.368
A			1.00 (reference)
G			1.03 (0.91–1.17)	0.602
rs1640827
TT	842	901	1.00 (reference)
TC	406	366	1.19 (1.00–1.41)	0.048
CC	52	33	1.69 (1.08–2.62)	0.021
T			1.00 (reference)
C			1.22 (1.06–1.41)	0.005
rs2241096
GG	762	772	1.00 (reference)
AG	471	456	1.05 (0.89–1.23)	0.585
AA	67	52	1.31 (0.89–1.90)	0.164
G			1.00 (reference)
A			1.08 (0.95–1.23)	0.231
rs17163737
GG	679	745	1.00 (reference)
GT	509	468	1.19 (1.01–1.40)	0.034
TT	112	87	1.41 (1.05–1.90)	0.023
G			1.00 (reference)
T			1.20 (1.06–1.35)	0.004
rs2241097
AA	974	990	1.00 (reference)
AC	307	296	1.05 (0.88–1.26)	0.571
CC	19	14	1.38 (0.69–2.76)	0.363
A			1.00 (reference)
C			1.07 (0.91–1.26)	0.384

*Adjusted for residence, smoking status and Helicobacter pylori infection